7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester

Names

[ Name ]:
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester

[Synonym ]:
N-Succinimidyl 7-Hydroxycoumarin-3-carboxylate
2,5-Dioxopyrrolidin-1-yl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate
1-{[(7-Hydroxy-2-oxo-2H-chromen-3-yl)carbonyl]oxy}-2,5-pyrrolidinedione
Umbelliferone-3-carboxylic acid N-succinimidyl ester
1-{[(7-Hydroxy-2-oxo-2H-chromen-3-yl)carbonyl]oxy}pyrrolidine-2,5-dione
2,5-Pyrrolidinedione, 1-[[(7-hydroxy-2-oxo-2H-1-benzopyran-3-yl)carbonyl]oxy]-
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester

Biological Activity

[Description]:

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Soh N, et, al. Phospholipid-linked coumarin: a fluorescent probe for sensing hydroxyl radicals in lipid membranes. Anal Sci. 2008 Feb;24(2):293-6.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
558.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₄H₉NO₇

[ Molecular Weight ]:
303.224

[ Flash Point ]:
291.8±32.9 °C

[ Exact Mass ]:
303.037903

[ PSA ]:
114.12000

[ LogP ]:
0.07

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.687

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Trans/cis (Z/E) photoisomerization of the chromophore of photoactive yellow protein is not a prerequisite for the initiation of the photocycle of this photoreceptor protein.

Proc. Natl. Acad. Sci. U. S. A. 95 , 7396-7401, (1998)

The chromophore of photoactive yellow protein (PYP) (i.e., 4-hydroxycinnamic acid) has been replaced by an analogue with a triple bond, rather than a double bond (by using 4-hydroxyphenylpropiolic aci...

Flow injection analysis of binding reaction between fluorescent lectin and cells.

Anal. Biochem. 269 , 230-235, (1999)

A fluorometric binding assay for lectin and yeast cells using the avidin-biotin system was previously reported (Y. Oda, M. Kinoshita, and K. Kakehi, Anal. Biochem. 254, 41-48, 1997). However, the true...