H-Tz-Bz-NH3Cl hydrochloride
Names
[ CAS No. ]:
1345866-68-3
[ Name ]:
H-Tz-Bz-NH3Cl hydrochloride
[Synonym ]:
(4-(1,2,4,5-TETRAZIN-3-YL)PHENYL)METHANAMINE HYDROCHLORIDE
Chemical & Physical Properties
[ Melting Point ]:
206-225°C (decomposition)
[ Molecular Formula ]:
C9H10ClN5
[ Molecular Weight ]:
223.662
[ Exact Mass ]:
223.062469
[ Storage condition ]:
?20°C
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H315-H319-H335
[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338
[ Hazard Codes ]:
T
[ Risk Phrases ]:
25-36/37/38
[ Safety Phrases ]:
26-45
[ RIDADR ]:
UN 2811 6.1 / PGIII
Articles
Bioconjug. Chem. 22 , 2263-2270, (2011)
1,2,4,5-Tetrazines have been established as effective dienes for inverse electron demand [4 + 2] Diels-Alder cycloaddition reactions with strained alkenes for over 50 years. Recently, this reaction pa...
Tetrazine-based cycloadditions: application to pretargeted live cell imaging.Bioconjug. Chem. 19 , 2297-2299, (2008)
Bioorthogonal tetrazine cycloadditions have been applied to live cell labeling. Tetrazines react irreversibly with the strained dienophile norbornene forming dihydropyrazine products and dinitrogen. T...
Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity.J. Am. Chem. Soc. 130 , 13518-13519, (2008)
Described is a bioorthogonal reaction that proceeds with unusually fast reaction rates without need for catalysis: the cycloaddition of s-tetrazine and trans-cyclooctene derivatives. The reactions tol...