γ-Secretase modulator 13

Names

[ Name ]:
γ-Secretase modulator 13

Biological Activity

[Description]:

γ-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 163 nM. γ-Secretase modulator 13 can be used in the study of Alzheimer's disease[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃FN₆S

[ Molecular Weight ]:
422.52

Related Compounds

γ-Secretase modulator 10
γ-secretase modulator 14a
γ-Secretase modulator 11
γ-Secretase modulator 11 hydrochloride
γ-Secretase modulator 12
gamma-secretase modulator 5
ethyl 4-methyl-2-({[4-(1H-pyrrol-1-yl)tetrahydro-2H-pyran-4-yl]acetyl}amino)-1,3-thiazole-5-carboxylate
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
3-(naphthalen-1-yl)-N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)propanamide
2,2-Bis(bromomethyl)propane-1,3-diol;tributyl stiborite
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
[1-(5-methoxy-1,3-dimethyl-1H-pyrazol-4-yl)cyclopropyl]methanamine