(S)-2-Aminobutane-1,4-dithiol hydrochloride

Names

[ CAS No. ]:
1363376-98-0

[ Name ]:
(S)-2-Aminobutane-1,4-dithiol hydrochloride

[Synonym ]:
DTBA. HCl
(2S)-2-amino-1,4-dimercaptobutane hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₄H₁₂ClNS₂

[ Molecular Weight ]:
173.72800

[ Exact Mass ]:
173.01000

[ PSA ]:
103.62000

[ LogP ]:
2.06570

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

A family of cationic polyamides for in vitro and in vivo gene transfection.

Acta Biomater. 22 , 120-30, (2015)

The purpose of this study is to develop biodegradable cationic polyamides for non-viral gene delivery and elucidate their structural effects on gene transfection activity. To this end, a group of nove...

Chemical de-conjugation for investigating the stability of small molecule drugs in antibody-drug conjugates.

J. Pharm. Biomed. Anal. 117 , 304-10, (2015)

Antibody-drug conjugates (ADCs) offer new therapeutic options for advanced cancer patients through precision killing with fewer side effects. The stability and efficacy of ADCs are closely related, em...

Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L.

PLoS ONE 10(1) , e0116898, (2015)

Phosphatase and tensin homologue deleted from chromosome ten (PTEN) is a lipid phosphatase tumor suppressor that is lost or inactivated in most human tumors. The enzyme catalyzes the hydrolysis of pho...