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3-Oxopomolic acid

Names

[ CAS No. ]:
13849-90-6

[ Name ]:
3-Oxopomolic acid

[Synonym ]:
(1R,2R,4aS,6aS,6bR,8aR,12aR,12bR,14bS)-1-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid
3-oxo-19α-hydroxyurs-12-en-28-oic acid
Pomonsaeure
3-oxo-19α-hydroxy-urs-12-en-28-oic acid

Biological Activity

[Description]:

Pomonic acid is a triterpenoid that significantly inhibits cholesterol ester accumulation and suppresses the acyl coenzyme A:cholesterol acyltransferase (ACAT) activity[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

ACAT[1]


[References]

[1]. Fujiwara Y, et al. Triterpenoids isolated from Zizyphus jujuba inhibit foam cell formation in macrophages. J Agric Food Chem. 2011 May 11;59(9):4544-52.  

Chemical & Physical Properties

[ Molecular Formula ]:
C30H46O4

[ Molecular Weight ]:
470.68400

[ Exact Mass ]:
470.34000

[ PSA ]:
74.60000

[ LogP ]:
6.41260


Related Compounds