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9-hydroxycanthin-6-one

Names

[ CAS No. ]:
138544-91-9

[ Name ]:
9-hydroxycanthin-6-one

[Synonym ]:
9-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
9-hydroxycanthin-6-one
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 9-hydroxy-

Biological Activity

[Description]:

9-Hydroxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 3.8 μM[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Thi Van Anh Tran, et al. NF-κB inhibitors from Eurycoma longifolia. J Nat Prod. 2014 Mar 28;77(3):483-8.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
410.1±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H8N2O2

[ Molecular Weight ]:
236.23

[ Flash Point ]:
201.8±28.7 °C

[ Exact Mass ]:
236.058578

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.796

[ Water Solubility ]:
Very slightly soluble (0.61 g/L) (25 ºC)


Related Compounds