ristocetin

Names

[ Name ]:
ristocetin

[Synonym ]:
ristocetin sulfate salt
EINECS 215-770-5

Biological Activity

[Description]:

Ristocetin is a glycopeptide antibiotic. Ristocetin induces platelet aggregation. Ristocetin can be used for Research of Von Willebrand’s disease[1][2].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Coller BS. The effects of ristocetin and von Willebrand factor on platelet electrophoretic mobility. J Clin Invest. 1978 May;61(5):1168-75.

[2]. Howard MA, et al. Ristocetin--a new tool in the investigation of platelet aggregation. Thromb Diath Haemorrh. 1971 Oct 31;26(2):362-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉₅H₁₁₀N₈O₄₄

[ Molecular Weight ]:
2067.92000

[ Exact Mass ]:
2066.66000

[ PSA ]:
816.22000

[ Index of Refraction ]:
1.783

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VJ8580000

CHEMICAL NAME :: Ristocetin

CAS REGISTRY NUMBER :: 1404-55-3

LAST UPDATED :: 199504

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 4,687,1956/1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4123 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 92 (estimated) No. of Female Employees: 86 (estimated)

Safety Information

[ Safety Phrases ]:
22-24/25

[ WGK Germany ]:
3

[ RTECS ]:
VJ8650000