Berberine (chloride hydrate)

Names

[ Name ]:
Berberine (chloride hydrate)

[Synonym ]:
9,10-Dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
Natural Yellow 18 Hydrate
BERBERIN HCL
7,8,13,13a-Tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium Chloride
9,10-Dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium chloride
Berberine chloride
1,3-Benzodioxolo[5,6-a]benzo[g]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
EINECS 211-195-9
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride
Berberin hydrochloride
1,3-benzodioxolo[5,6-a]benzo[g]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
BBR
UMBELLATINE
Berberine Chloride Hydrate
5,6-Dihydro-9,10-dimethoxybenzo[g]1,3-benzodioxolo[5,6-a]quinolizinium Chloride
BERBERINE HCL
MFCD00011939
Berberine chloride std.
Natural Yellow 18
Berberine (chloride hydrate)

Chemical & Physical Properties

[ Melting Point ]:
204-206 °C (dec.)

[ Molecular Formula ]:
C₂₀H₁₈ClNO₄

[ Molecular Weight ]:
371.814

[ Exact Mass ]:
371.092438

[ PSA ]:
40.80000

[ LogP ]:
0.10030

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DR9866400

[ HS Code ]:
3003409000

Customs

[ HS Code ]: 3003409000

Articles

Berberine blocks the relapse of Clostridium difficile infection in C57BL/6 mice after standard vancomycin treatment.

Antimicrob. Agents Chemother. 59 , 3726-35, (2015)

Vancomycin is a preferred antibiotic for treating Clostridium difficile infection (CDI) and has been associated with a rate of recurrence of CDI of as high as 20% in treated patients. Recent studies h...

Synergistic topical application of salt-processed Phellodendron amurense and Sanguisorba officinalis Linne alleviates atopic dermatitis symptoms by reducing levels of immunoglobulin E and pro-inflammatory cytokines in NC/Nga mice.

Mol. Med. Report. 12 , 7657-64, (2015)

Atopic dermatitis is a chronic inflammatory skin disease, and salt-processed Phellodendron amurense (CPE) and Sanguisorba officinalis Linne (SOE) are widely used as anti-inflammatory agents in Asia. T...

Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway.

Mol. Cancer Ther. 14(2) , 355-63, (2015)

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor and has a poor prognosis. We, here, report a potent antitumor effect of berberine, an isoquinoline alkaloid, on GBM. Berb...