α-Conotoxin MrIC

Names

[ CAS No. ]:
1417816-41-1

[ Name ]:
α-Conotoxin MrIC

Biological Activity

[Description]:

α-Conotoxin MrIC is an α7nAChR biased agonist. α-Conotoxin MrIC exclusively activates α7nAChR regulated by type II positive allosteric modulators, including PNU120596. α-Conotoxin MrIC can be used to study neurological diseases and also to probe the pharmacological properties of α7nAChR[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR
Signaling Pathways >> Neuronal Signaling >> nAChR
Research Areas >> Neurological Disease

[Target]

α7nAChR[1].


[References]

[1]. Mueller A, et al. α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochem Pharmacol. 2015 Mar 15;94(2):155-63.  

Chemical & Physical Properties

[ Molecular Formula ]:
C74H111N23O24S4

[ Molecular Weight ]:
1835.07

Related Compounds