Methyl 3-aminocrotonate

Names

[ Name ]:
Methyl 3-aminocrotonate

[Synonym ]:
methyl 3-aminobut-2-enoate
(E)-methyl 3-aminobut-2-enoate
3-aminobut-2-enoic acid methyl ester
Methyl 3-aminocroton
MFCD06659463
(E)-3-Amino-but-2-enoic acid methyl ester
2-Butenoic acid, 3-amino-, methyl ester
Methyl 3-Amino-2-butenoate
Methyl (2E)-3-amino-2-butenoate
METHYL 4-AMINOCROTONATE
Methyl 3-iminobutyrate
3-Amino-2-Butenoic Acid Methyl Ester
3-Aminocrotonic Acid Methyl Ester
methyl3-aminocrotonoate
2-Butenoic acid, 3-amino-, methyl ester, (2E)-
EINECS 238-056-5
Nifedipine Impurity 5

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
194.1±13.0 °C at 760 mmHg

[ Melting Point ]:
81-83 °C(lit.)

[ Molecular Formula ]:
C₅H₉NO₂

[ Molecular Weight ]:
115.131

[ Flash Point ]:
65.3±17.4 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
52.32000

[ LogP ]:
-0.14

[ Vapour Pressure ]:
0.4±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.457

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H332

[ Precautionary Statements ]:
P261-P301 + P312 + P330

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
EM9092500

[ HS Code ]:
29224995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Quantitative reaction cascades of ninhydrin in the solid state.

Chemistry 8(3) , 594-600, (2002)

Crystalline ninhydrin (1) undergoes waste-free solid-state cascade reactions with dimedone, L-proline, three o-phenylenediamines, o-mercaptoaniline, two ureas, three thioureas, and methyl 3-aminocroto...

Synthesis of a new series of 4-aryl-1,4-dihydropyridines with calcium channel blocking and vasodilatory activity.

Pharmazie 61(5) , 400-5, (2006)

Synthesis of a new series of 4-aryl-1,4-dihydropyridines possessing potential calcium channel blocking activity along with good vasodilatory profile is reported. The compounds were synthesized using m...