4-Epioxytetracycline

Names

[ Name ]:
4-Epioxytetracycline

[Synonym ]:
Oxy-tetracyclin
MFCD00062825
Hydroxy Quatrimycin
4-epi-Oxytetracycline
UNII-73VON8SRY5
4-Epioxytetracycline,‘can be used as secondary standard‘
4-epioxytetracyline

Biological Activity

[Description]:

4-Epioxytetracycline, the degradation product of Oxytetracycline (OTC), can be found in swine manure compost and wastewater[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Wu X, et, al. The behavior of tetracyclines and their degradation products during swine manure composting. Bioresour Technol. 2011 May;102(10):5924-31.

[2]. Çelik A, et, al. Degradation of oxytetracycline under autotrophic nitrifying conditions in a membrane aerated biofilm reactor and community fingerprinting. J Hazard Mater. 2018 Aug 15;356:26-33.

Chemical & Physical Properties

[ Boiling Point ]:
727.8ºC at 760mmHg

[ Melting Point ]:
168ºC

[ Molecular Formula ]:
C₂₂H₂₄N₂O₉

[ Molecular Weight ]:
460.43400

[ Flash Point ]:
394ºC

[ Exact Mass ]:
460.14800

[ PSA ]:
202.84000

[ Appearance of Characters ]:
Powder | Greenish-beige to brownish

[ Vapour Pressure ]:
3.09E-22mmHg at 25°C

[ Storage condition ]:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29413020

Articles

Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds.

J. AOAC Int. 95(4) , 1010-5, (2012)

A selective and accurate LC/MS/MS method for the simultaneous determination of chlortetracycline (CTC), oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) in animal feeds was developed. Sa...

Heterologous expression and manipulation of three tetracycline biosynthetic pathways.

Angew. Chem. Int. Ed. Engl. 51(44) , 11136-40, (2012)

A very accommodating host: Three tetracycline biosynthetic pathways were overexpressed and manipulated in the heterologous host Streptomyces lividans K4-114. Through the inactivation of various genes ...

Topical steroids for chronic wounds displaying abnormal inflammation.

Ann. R. Coll. Surg. Engl. 95(4) , 291-6, (2013)

Chronic, non-healing wounds are often characterised by an excessive, and detrimental, inflammatory response. We review our experience of using a combined topical steroid, antibiotic and antifungal pre...