PR-893
Names
[ CAS No. ]:
1426305-23-8
[ Name ]:
PR-893
Biological Activity
[Description]:
A potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely.
[References]
References 1. Parlati F, et al. Blood. 2009 Oct 15;114(16):3439-47. 2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209. View Related Products by Target Proteasome
Chemical & Physical Properties
[ Molecular Formula ]:
C23H34N4O7
[ Molecular Weight ]:
478.546