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n-acetyl-n-acetoxy-4-chlorobenzenesulfonamide

Names

[ CAS No. ]:
142867-52-5

[ Name ]:
n-acetyl-n-acetoxy-4-chlorobenzenesulfonamide

[Synonym ]:
Tocris-0722
N-acetyl-N-acetoxy-4-chlorobenzenesulphonamide
N-ACETYL-N-ACETOXY-4-CHLOROBENZENESULFONAMIDE
N-Acetoxy-N-acetyl-4-chlorobenzenesulfonamide
A9584_ALDRICH

Chemical & Physical Properties

[ Density]:
1.454 g/cm3

[ Boiling Point ]:
401.4ºC at 760 mmHg

[ Melting Point ]:
119-122ºC

[ Molecular Formula ]:
C10H10ClNO5S

[ Molecular Weight ]:
291.70800

[ Flash Point ]:
196.6ºC

[ Exact Mass ]:
290.99700

[ PSA ]:
89.13000

[ LogP ]:
2.43610

[ Vapour Pressure ]:
1.18E-06mmHg at 25°C

[ Index of Refraction ]:
1.559

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase.

J. Med. Chem. 35 , 3648, (1992)

In the preceding paper, analogs of chlorpropamide with an OMe substituent on the sulfonamide nitrogen were shown to inhibit aldehyde dehydrogenase (AlDH), and it was postulated that these compounds we...

N,O-diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties.

Biochem. Biophys. Res. Commun. 187 , 1367, (1992)

N,O-Diacylated-N-hydroxyarylsulfonamides are capable of slowly releasing nitroxyl (HNO) by simple, non-enzymatic hydrolysis in Krebs solution at 37 degrees C. Release of nitric oxide (NO) was not seen...


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Related Compounds