1-Chloro-2,4-difluorobenzene

Names

[ Name ]:
1-Chloro-2,4-difluorobenzene

[Synonym ]:
2,4-Difluorochlorobenzene
1-Chloro-2,4-difluorobenzene
Benzene,1-chloro-2,4-difluoro-
GR CF EF
Benzene, 1-chloro-2,4-difluoro-
MFCD00042569
1-chloro-2,4-Difluorobenze

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
127.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-26 °C

[ Molecular Formula ]:
C₆H₃ClF₂

[ Molecular Weight ]:
148.538

[ Flash Point ]:
32.8±0.0 °C

[ Exact Mass ]:
147.989136

[ LogP ]:
3.01

[ Vapour Pressure ]:
13.8±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.479

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi,F:Flammable;

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S16-S26-S36/37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
2

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis of benzonorbornadienes: regioselective benzyne formation.

J. Org. Chem. 66(9) , 2932-6, (2001)

This report details the synthesis of several benzonorbornadienes by Diels--Alder cycloaddition of cyclopentadiene derivatives with substituted benzyne intermediates, which were generated by low-temper...

Azo group-assisted nucleophilic aromatic substitutions in haloarene derivatives: preparation of substituted 1-iodo-2,6-bispropylthiobenzenes.

J. Org. Chem. 69(6) , 1967-71, (2004)

Aryldiazo substituents were used in nucleophilic aromatic substitution reactions of halogens. The Ph-N=N- group activates ortho fluorine atoms toward alkylthiolation under mild conditions. In contrast...