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Imatinib carbaldehyde

Names

[ CAS No. ]:
1436868-85-7

[ Name ]:
Imatinib carbaldehyde

Biological Activity

[Description]:

PROTAC ABL binding moiety 1, the Imatinib (ABL inhibitor) moiety, binds to IAP ligand via a linker to form SNIPER[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H29N7O2

[ Molecular Weight ]:
507.59