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Benzamide,2-(acetyloxy)-N-(4-chlorophenyl)-3,5-diiodo-

Names

[ CAS No. ]:
14437-41-3

[ Name ]:
Benzamide,2-(acetyloxy)-N-(4-chlorophenyl)-3,5-diiodo-

[Synonym ]:
2-Acetoxy-3,5-diiodo-4'-chlorobenzanilide
Tremerad
CN 59,567
CLIOXANIDE
2-Acetoxy-4'-chlor-3.5-diiod-benzanilid
2-Acetoxy-4'-chloro-3,5-di-iodobenzanilide
4'-Chloro-3,5-diiodosalicylanilide acetate
SYD 230

Chemical & Physical Properties

[ Density]:
2.066g/cm3

[ Boiling Point ]:
496.8ºC at 760mmHg

[ Molecular Formula ]:
C15H10ClI2NO3

[ Molecular Weight ]:
541.50700

[ Flash Point ]:
254.3ºC

[ Exact Mass ]:
540.84400

[ PSA ]:
55.40000

[ LogP ]:
4.79980

[ Vapour Pressure ]:
5.24E-10mmHg at 25°C

[ Index of Refraction ]:
1.714

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN7885000
CHEMICAL NAME :
Salicylanilide, 4'-chloro-3,5-diiodo-, acetate ester
CAS REGISTRY NUMBER :
14437-41-3
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C15-H10-Cl-I2-N-O3
MOLECULAR WEIGHT :
541.51
WISWESSER LINE NOTATION :
IR CI DOV1 EVMR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AUVJA2 Australian Veterinary Journal. (Australian Veterinary Assoc., Executive Director, 134-136 Hampden Road, Artarmon, N.S.W., Australia) V.2- 1927- Volume(issue)/page/year: 46,297,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AUVJA2 Australian Veterinary Journal. (Australian Veterinary Assoc., Executive Director, 134-136 Hampden Road, Artarmon, N.S.W., Australia) V.2- 1927- Volume(issue)/page/year: 46,297,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
720 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - acute pulmonary edema Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
AUVJA2 Australian Veterinary Journal. (Australian Veterinary Assoc., Executive Director, 134-136 Hampden Road, Artarmon, N.S.W., Australia) V.2- 1927- Volume(issue)/page/year: 46,297,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
414 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - acute pulmonary edema Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
AUVJA2 Australian Veterinary Journal. (Australian Veterinary Assoc., Executive Director, 134-136 Hampden Road, Artarmon, N.S.W., Australia) V.2- 1927- Volume(issue)/page/year: 46,297,1970 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - cattle
DOSE/DURATION :
250 mg/kg/5D-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
AUVJA2 Australian Veterinary Journal. (Australian Veterinary Assoc., Executive Director, 134-136 Hampden Road, Artarmon, N.S.W., Australia) V.2- 1927- Volume(issue)/page/year: 46,297,1970

Synthetic Route


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