3,4-Difluorobenzenesulfonyl chloride

Names

[ Name ]:
3,4-Difluorobenzenesulfonyl chloride

[Synonym ]:
Benzenesulfonyl chloride, 3,4-difluoro-
WSGR CF DF
MFCD00153120
3,4-Difluorobenzenesulfonyl chloride
3,4-Difluorobenzene-1-sulfonyl chloride

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
258.1±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₃ClF₂O₂S

[ Molecular Weight ]:
212.602

[ Flash Point ]:
109.9±21.8 °C

[ Exact Mass ]:
211.951035

[ PSA ]:
42.52000

[ LogP ]:
2.63

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.516

[ Storage condition ]:
2~8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Palladium-catalyzed direct desulfitative C2 arylations of 3-halo-N-protected indoles using (hetero)arenesulfonyl chlorides.

Org. Biomol. Chem. 14(21) , 4947-56, (2016)

The direct arylation of N-protected 3-haloindole derivatives with benzenesulfonyl chlorides as coupling partners using 5 mol% of bis(acetonitrile)dichloropalladium(ii) catalyst and lithium carbonate a...