3-Amino-4(3H)-quinazolinone

Names

[ Name ]:
3-Amino-4(3H)-quinazolinone

[Synonym ]:
3-amino-3H-quinazolin-4-one
3-amino-3,4-dihydroquinazolin-4-one
3-Amino-3H-chinazolin-4-on
3-amino-4-oxo-3,4-dihydroquinazoline
MFCD01038386
3-Amino-4(3H)-quinazolinone

Chemical & Physical Properties

[ Density]:
1.41g/cm3

[ Boiling Point ]:
348.9ºC at 760 mmHg

[ Melting Point ]:
209-213ºC(lit.)

[ Molecular Formula ]:
C₈H₇N₃O

[ Molecular Weight ]:
161.16100

[ Flash Point ]:
164.8ºC

[ Exact Mass ]:
161.05900

[ PSA ]:
60.91000

[ LogP ]:
0.69150

[ Vapour Pressure ]:
4.87E-05mmHg at 25°C

[ Index of Refraction ]:
1.702

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA2330000

CHEMICAL NAME :: 4(3H)-Quinazolinone, 3-amino-

CAS REGISTRY NUMBER :: 14663-46-8

BEILSTEIN REFERENCE NO. :: 0131407

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H7-N3-O

MOLECULAR WEIGHT :: 161.18

WISWESSER LINE NOTATION :: T66 BVN ENJ CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 2,202,1967

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%