4-(aziridin-1-yl)-6-chloropyrimidine

Names

[ Name ]:
4-(aziridin-1-yl)-6-chloropyrimidine

[Synonym ]:
Pyrimidine,4-(1-aziridinyl)-6-chloro
4-Ethyleneimino-6-chloropyrimidine
4-(1-Aziridinyl)-6-chloropyrimidine
4-aziridin-1-yl-6-chloro-pyrimidine

Chemical & Physical Properties

[ Density]:
1.455g/cm3

[ Boiling Point ]:
303.4ºC at 760mmHg

[ Molecular Formula ]:
C₆H₆ClN₃

[ Molecular Weight ]:
155.58500

[ Flash Point ]:
137.3ºC

[ Exact Mass ]:
155.02500

[ PSA ]:
28.79000

[ LogP ]:
1.01500

[ Vapour Pressure ]:
0.000933mmHg at 25°C

[ Index of Refraction ]:
1.635

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV6803000

CHEMICAL NAME :: Pyrimidine, 4-(1-aziridinyl)-6-chloro-

CAS REGISTRY NUMBER :: 14673-04-2

BEILSTEIN REFERENCE NO. :: 0908490

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H6-Cl-N3

MOLECULAR WEIGHT :: 155.60

WISWESSER LINE NOTATION :: T6N CNJ DG F- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 96 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 245 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970