4′-Fluoro-2′-hydroxyacetophenone
Names
[ CAS No. ]:
1481-27-2
[ Name ]:
4′-Fluoro-2′-hydroxyacetophenone
[Synonym ]:
1-Acetyl-4-fluoro-2-hydroxybenzene
4′-Fluoro-2′-hydroxyacetophenone
Ethanone, 1-(4-fluoro-2-hydroxyphenyl)-
1-(4-Fluoro-2-hydroxyphenyl)ethanone
4-Fluoro-2-Hydroxyacetophenone
MFCD00143203
QR CF FV1
1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one
4'-Fluoro-2'-hydroxyacetophenone
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
237.5±20.0 °C at 760 mmHg
[ Melting Point ]:
32-34°C
[ Molecular Formula ]:
C8H7FO2
[ Molecular Weight ]:
154.138
[ Flash Point ]:
97.4±21.8 °C
[ Exact Mass ]:
154.043015
[ PSA ]:
37.30000
[ LogP ]:
2.42
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.530
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36/37/39-S36
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2914399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
J. Enzyme Inhib. Med. Chem. , 1-8, (2014)
In an effort to develop safe and potent anti-inflammatory agents, a series of novel 4'-fluoro-2'-hydroxychalcones 5a-d and their dihydropyrazole derivatives 6a-d was prepared. It was synthesized via a...
19F NMR study on the biological Baeyer-Villiger oxidation of acetophenones.J. Ind. Microbiol. Biotechnol. 26(1-2) , 35-42, (2001)
The biological Baeyer-Villiger oxidation of acetophenones was studied by 19F nuclear magnetic resonance (NMR). The 19F NMR method was used to characterise the time-dependent conversion of various fluo...
J. Heterocycl. Chem. 30 , 445, (1993)