Methylenebis(Phosphonic Dichloride)

[ Density]:
1.798g/cm3

[ Boiling Point ]:
329ºC at 760 mmHg

[ Melting Point ]:
102-104ºC(lit.)

[ Molecular Formula ]:
CH₂Cl₄O₂P₂

[ Molecular Weight ]:
249.78500

[ Flash Point ]:
152.8ºC

[ Exact Mass ]:
247.82800

[ PSA ]:
53.76000

[ LogP ]:
4.28530

[ Vapour Pressure ]:
0.00035mmHg at 25°C

[ Index of Refraction ]:
1.485

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
14-34

[ Safety Phrases ]:
26-27-36/37/39-45

[ RIDADR ]:
UN 3261 8/PG 1

[ WGK Germany ]:
3

[ HS Code ]:
2931900090

Click to get detail synthetic route

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

SYNTHESIS OF SYMMETRICAL METHYLENEBIS(ALKYL HYDROGEN PHOSPHONATES) BY SELECTIVE CLEAVAGE OF METHYLENEBIS(DIALKYL PHOSPHONATES) WITH MORPHOLINE.

Synth. Commun. 34(2) , 331-344, (2004)

The preparation of partial esters of methylenebisphosphonic acids has been of recent interest due to their potential therapeutic applications. This paper describes a convenient method to prepare symme...

Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.

J. Med. Chem. 45(3) , 703-12, (2002)

Novel mycophenolic adenine dinucleotide (MAD) analogues have been prepared as potential inhibitors of inosine monophosphate dehydrogenase (IMPDH). MAD analogues resemble nicotinamide adenine dinucleot...

A direct method for the synthesis of nucleoside 5'-methylenebis (phosphonate) s from nucleosides. Kalek M, et al.

Tetrahedron Lett. 46(!4) , 2417-21, (2005)

More Articles