2-Phenylacetic dithioperoxyanhydride

Names

[ Name ]:
2-Phenylacetic dithioperoxyanhydride

[Synonym ]:
Bis(phenylacetyl) Disulfide
PADS
bis-phenylacetyl-disulfane
2-Phenylacetic dithioperoxyanhydride
DIPHENYLACETYL DISULFIDE
Diphenacetyldisulfid
Phenylacetyl Disulfide
PHENYLACETYL DISULPHIDE
Bis-phenylacetyl-disulfan
MFCD03453048
Dibenzyldithioperoxyanhydride
Bis-phenylacetyl-disulfid
Phenylacetyldisulfide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
481.1±48.0 °C at 760 mmHg

[ Melting Point ]:
59-63 °C(lit.)

[ Molecular Formula ]:
C₁₆H₁₄O₂S₂

[ Molecular Weight ]:
302.411

[ Flash Point ]:
210.1±19.6 °C

[ Exact Mass ]:
302.043518

[ PSA ]:
84.74000

[ LogP ]:
4.68

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.638

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Synthesis and biological activity of PTEN-resistant analogues of phosphatidylinositol 3,4,5-trisphosphate.

J. Am. Chem. Soc. 128(51) , 16464-5, (2006)

The activation of phosphatidylinositol 3-kinase (PI 3-K) and subsequent production of PtdIns(3,4,5)P3 launches a signal transduction cascade that impinges on a plethora of downstream effects on cell p...

Synthesis of antisense oligonucleotides: Replacement of 3H-1, 2-benzodithiol-3-one 1, 1-dioxide (Beaucage reagent) with phenylacetyl disulfide (PADS) as efficient sulfurization reagent: From bench to bulk manufacture of active pharmaceutical ingredient. Cheruvallath ZS, et al.

Org. Process Res. Dev. 4(3) , 199-204, (2000)

Use of phenylacetyl disulfide (PADS) in the synthesis of oligodeoxyribonucleotide phosphorothioates. Cheruvallath ZS, et al.

Nucleosides Nucleotides Nucleic Acids 18(3) , 485-492, (1999)