AC 253

Names

[ Name ]:
AC 253

Biological Activity

[Description]:

AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂₂H₁₉₆N₄₀O₃₉

[ Molecular Weight ]:
2847.11

[ Storage condition ]:
-20°C

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