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Annexin A1 (1-25) (dephosphorylated) (human) trifluoroacetate salt

Names

[ CAS No. ]:
151988-33-9

[ Name ]:
Annexin A1 (1-25) (dephosphorylated) (human) trifluoroacetate salt

[Synonym ]:
Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH

Biological Activity

[Description]:

Ac2-26, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. Ac2-26 also decreases AnxA1 protein expression, inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Liao WI, et al. Ac2-26, an Annexin A1 Peptide, Attenuates Ischemia-Reperfusion-Induced Acute Lung Injury. Int J Mol Sci. 2017 Aug 15;18(8). pii: E1771.

Chemical & Physical Properties

[ Molecular Formula ]:
C141H210N32O44S

[ Molecular Weight ]:
3089.43

[ Exact Mass ]:
3087.49000

[ PSA ]:
1277.48000

[ LogP ]:
5.82300


Related Compounds