A 366

Names

[ CAS No. ]:
1527503-11-2

[ Name ]:
A 366

[Synonym ]:
5'-methoxy-6'-(3-(pyrrolidin-1-yl)propoxy)spiro[cyclobutane-1,3'-indol]-2'-amine

[Description]:

A-366 is a potent histone methyltransferase G9a inhibitor with an IC50 of 3.3 nM.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

Research Areas >> Cancer

[References]

[Related Small Molecules]

GSK126 | Tazemetostat (EPZ-6438) | UNC 0642 | GSK343 | Pinometostat (EPZ5676) | 3-Deazaneplanocin A (hydrochloride) | Pemrametostat (GSK3326595) | UNC1999 | BIX-01294 | EPZ031686 | AZ505 (ditrifluoroacetate) | MS023 | EPZ 004777 | EPZ015666 | EPZ015866(GSK591)

[ Molecular Formula ]:
C₁₉H₂₇N₃O₂

[ Molecular Weight ]:
329.43700

[ Exact Mass ]:
329.21000

[ PSA ]:
60.08000

[ LogP ]:
3.05770

[ Storage condition ]:
-20℃

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273-P391

[ RIDADR ]:
UN 3077 9 / PGIII