(2S,3S,4R,5R)-5-[6-[(4-amino-3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Names
[ CAS No. ]:
152918-27-9
[ Name ]:
(2S,3S,4R,5R)-5-[6-[(4-amino-3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
[Synonym ]:
3-Iodo-4-aminobenzyl-5'-N-methylcarboxamidoadenosine
I-AB-MECA
Chemical & Physical Properties
[ Density]:
2.066g/cm3
[ Molecular Formula ]:
C18H20IN7O4
[ Molecular Weight ]:
525.30000
[ Exact Mass ]:
525.06200
[ PSA ]:
163.93000
[ LogP ]:
1.48490
[ Index of Refraction ]:
1.842
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Mol. Pharmacol. 45 , 978-982, (1994)
The rat A3 adenosine receptor (AR) is a recently characterized AR subtype cloned from testis and brain cDNA libraries. N6-2-(4-Amino-3-[125I]iodophenyl)ethyladenosine, a high affinity A1AR agonist, ha...
A role for central A3-adenosine receptors. Mediation of behavioral depressant effects.FEBS Lett. 336 , 57-60, (1993)
The behavioral effects of a selective A3 adenosine receptor agonist 3-IB-MECA (N6-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine) in mice and the localization of radioligand binding sites in mouse bra...
The effects of adenosine A3 receptor stimulation on seizures in mice.Eur. J. Pharmacol. 275 , 23-29, (1995)
We have previously shown that acute preischemic adenosine A3 receptor stimulation results in an increased postischemic damage, while chronic stimulation of this receptor diminishes it. Since several p...