2-Phenanthrenecarboxylicacid, 1-ethyl-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, (1R,2S)-rel-
Names
[ CAS No. ]:
15372-34-6
[ Name ]:
2-Phenanthrenecarboxylicacid, 1-ethyl-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, (1R,2S)-rel-
[Synonym ]:
rac-3-Methoxy-16.17-seco-oestrapentaen-(A.B)-saeure-(18)
2-Phenanthrenecarboxylic acid,1-ethyl-1,2,3,4-tetrahydro-7-methoxy-2-methyl-,cis-(.+-.)
(+-)-7-Methoxy-2t-methyl-1r-aethyl-1.2.3.4-tetrahydro-phenanthren-carbonsaeure-(2c)
Bdda me
1-Ethyl-7-methoxy-2-methyl-1,2,3,4-tetrahydro-2-phenanthrenecarboxylic acid
(+-)-1c-Aethyl-7-methoxy-2-methyl-1,2,3,4-tetrahydro-phenanthren-2r-carbonsaeure
(+-)-7-Methoxy-2t-methyl-1r-ethyl-1,2,3,4-tetrahydro-phenanthren-carbonsaeure-(2c),'(+-)-O-Methyl-cis-bisdehydrodoisynolsaeure
rac-3-Methoxy-16.17-seco-oestrapentaen-(1.3.5.7.9)-saeure-(18)
Dl-cis-bisdehydrodoisynolic acid methyl ether
Doisynoestrol
(+-)-1c-ethyl-7-methoxy-2-methyl-1,2,3,4-tetrahydro-phenanthrene-2r-carboxylic acid
Chemical & Physical Properties
[ Density]:
1.136g/cm3
[ Boiling Point ]:
480ºC at 760mmHg
[ Molecular Formula ]:
C19H22O3
[ Molecular Weight ]:
298.37600
[ Flash Point ]:
172.4ºC
[ Exact Mass ]:
298.15700
[ PSA ]:
46.53000
[ LogP ]:
4.37910
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.582
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VS3040000
- CHEMICAL NAME :
- 16,17-Seco-13-alpha-estra-1,3,5,7,9-pentaen-17-oic acid, 3-methoxy-, (+-)-
- CAS REGISTRY NUMBER :
- 15372-34-6
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H22-O3
- MOLECULAR WEIGHT :
- 298.41
- WISWESSER LINE NOTATION :
- L B666&&TJ EO1 K2 LVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 17500 ng/kg
- SEX/DURATION :
- female 7 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 3,387,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 300 ug/kg
- SEX/DURATION :
- female 7-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 3,387,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2400 ug/kg
- SEX/DURATION :
- female 6 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 4,15,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 mg/kg
- SEX/DURATION :
- female 1-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 115,101,1973