Calcein (mixture of isomers)

Names

[ Name ]:
Calcein (mixture of isomers)

[Synonym ]:
EINECS 215-957-1
V0YM2B16TS
2,2',2'',2'''-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-2',7'-diyl)bis(methylenenitrilo)]tetraacetic acid
calcein
2,2',2'',2'''-[(3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-2',7'-diyl)bis(methanediylnitrilo)]tetraacetic acid
MFCD00005049
oftasceinum [INN_la]
oftasceine

Biological Activity

[Description]:

Calcein mixture of isomers is a calcium-dependent fluorescent molecule. Calcein mixture of isomers can be used to study bone metabolism (in vivo) and to stain depressed areas (in vitro). Calcein mixture of isomers can also be used for fluorometry and EDTA titration of calcium.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
952.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₂₆N₂O₁₃

[ Molecular Weight ]:
622.533

[ Flash Point ]:
530.0±34.3 °C

[ Exact Mass ]:
622.143494

[ LogP ]:
1.56

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.775

[ Water Solubility ]:
NaOH: soluble50mg/mL

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Comparative in vitro study on magnetic iron oxide nanoparticles for MRI tracking of adipose tissue-derived progenitor cells.

PLoS ONE 9(9) , e108055, (2014)

Magnetic resonance imaging (MRI) using measurement of the transverse relaxation time (R2*) is to be considered as a promising approach for cell tracking experiments to evaluate the fate of transplante...

Desmethyl bosentan displays a similar in vitro interaction profile as bosentan.

Pulm. Pharmacol. Ther. 30 , 80-6, (2015)

The endothelin-1 receptor antagonists bosentan and ambrisentan used for the treatment of pulmonary arterial hypertension remarkably differ in their potential to act as perpetrators in pharmacokinetic ...

Covalent and stable CuAAC modification of silicon surfaces for control of cell adhesion.

ChemBioChem. 16(5) , 782-91, (2015)

Stable primary functionalization of metal surfaces plays a significant role in reliable secondary attachment of complex functional molecules used for the interfacing of metal objects and nanomaterials...