BMT-090605

Names

[ Name ]:
BMT-090605

Biological Activity

[Description]:

BMT-090605 (BMT 090605, BMT090605) is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50 0.6 nM; weakly inhibits BIKE and GAK with IC50 of 45 and 60 nM, respectively.

[References]

References 1. Kostich W, et al. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86. View Related Products by Target AP2-associated Kinase 1 (AAK1)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₄N₄O₂

[ Molecular Weight ]:
364.449

Related Compounds

BMT-090605 hydrochloride
BMT-124110
BMT-145027
BMT-297376
BMT-046091
BMT-052
2,5-dichloro-N-((4-methoxy-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-yl)methyl)thiophene-3-carboxamide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
3-Ethyl-1-(2-ethynylphenyl)urea
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
2-cyclopropyl-N-(oxan-4-yl)pyrimidin-4-amine
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
N-(1-Benzyl-4-cyanopiperidin-4-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-7-carboxamide