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9,10-Dimethoxycanthin-6-one

Names

[ CAS No. ]:
155861-51-1

[ Name ]:
9,10-Dimethoxycanthin-6-one

[Synonym ]:
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 9,10-dimethoxy-
9,10-Dimethoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
9,10-Dimethoxycanthin-6-one

Biological Activity

[Description]:

9,10-Dimethoxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 19.5 μM[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Thi Van Anh Tran, et al. NF-κB inhibitors from Eurycoma longifolia. J Nat Prod. 2014 Mar 28;77(3):483-8.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
405.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H12N2O3

[ Molecular Weight ]:
280.28

[ Flash Point ]:
199.1±28.7 °C

[ Exact Mass ]:
280.084778

[ LogP ]:
2.63

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.688

[ Water Solubility ]:
Very slightly soluble (0.31 g/L) (25 ºC)

Related Compounds