FV-162

Names

[ Name ]:
FV-162

Biological Activity

[Description]:

A potent, orally bioavailable, irreversible proteasome inhibitor with potent antimyeloma activity (IC50<60 nM); induces rapid, irreversible inhibition of chymotrypsin-like proteasome activity in murine red blood cells and inhibits tumor growth in myeloma xenograft model.

[References]

References 1. Wang Z, et al. Cell Death Dis. 2015 Jul 9;6:e1815. View Related Products by Target Proteasome

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₈F₄N₄O₇S

[ Molecular Weight ]:
604.574

Related Compounds

FV-100
thulium-162
holmium-162
ytterbium-162
SNC 162
ML-162
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine