Phenylphosphonic acid

Names

[ Name ]:
Phenylphosphonic acid

[Synonym ]:
Phenylphosphonic acid
Phenyl-phosphonic acid
EINECS 212-220-6
Phosphonic acid, phenyl-
phenyl phosphonic acid
Phosphonic acid,phenyl
PhP(O)(OH)2
MFCD00002067
monophenylphosphonic acid
Benzene phosphonic acid
Benzenephosphonic acid
EINECS 216-388-1

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
353.7±25.0 °C at 760 mmHg

[ Melting Point ]:
162-164 °C(lit.)

[ Molecular Formula ]:
C₆H₇O₃P

[ Molecular Weight ]:
158.092

[ Flash Point ]:
167.7±23.2 °C

[ Exact Mass ]:
158.013275

[ PSA ]:
67.34000

[ LogP ]:
0.54

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.572

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
40.4 g/100 mL (25 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TA0350000

CHEMICAL NAME :: Phosphonic acid, phenyl-

CAS REGISTRY NUMBER :: 1571-33-1

BEILSTEIN REFERENCE NO. :: 2245168

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C6-H7-O3-P

MOLECULAR WEIGHT :: 158.10

WISWESSER LINE NOTATION :: QPQO&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545369 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Gastrointestinal - other changes Blood - hemorrhage

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545369

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 110 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 2,55,1950 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84171 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 104 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S39-S37/39

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TD4393000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2931900090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Molecularly imprinted polymer dedicated to the extraction of glyphosate in natural waters.

J. Chromatogr. A. 1361 , 1-8, (2014)

Three molecularly imprinted polymers (MIPs) have been synthesized in order to bind efficiently glyphosate (GLY) in natural waters (mineral and underground). Since the target analyte is polar and hydro...

Specific recognition of tyrosine-phosphorylated peptides by epitope imprinting of phenylphosphonic acid

J. Chromatogr. A. 1293 , 85-91, (2013)

• We developed an epitope imprinting approach for pTyr peptide capture by MIPs. • PPA, a characteristic component of phenylphosphate group was used as template. • MIPs showed good selectivity and clea...

Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates.

Bioorg. Med. Chem. Lett. 15 , 1683-6, (2005)

The interaction of five human carbonic anhydrase (hCA, EC 4.2.1.1) isozymes, that is, hCA I, II, IV, V, and IX with a small library of phosphonic acids/organic phosphates, including methylphosphonic a...