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Afasevikumab

Names

[ CAS No. ]:
1589503-30-9

[ Name ]:
Afasevikumab

Biological Activity

[Description]:

Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[In Vitro]

Afasevikumab 由 N 末端 IL-17F 特异性部分、结合 IL-17A 和 IL-17F 的 a-C 末端部分以及结合人血清白蛋白的中心部分组成[1]。

[References]

[1]. Andrea Chiricozzi, et al. Emerging treatment options for the treatment of moderate to severe plaque psoriasis and psoriatic arthritis: evaluating bimekizumab and its therapeutic potential. Psoriasis (Auckl). 2019 May 24;9:29-35.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds