1-Bromo-2-isocyanatobenzene

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
281.6±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₄BrNO

[ Molecular Weight ]:
198.017

[ Flash Point ]:
92.2±22.6 °C

[ Exact Mass ]:
196.947617

[ PSA ]:
29.43000

[ LogP ]:
3.30

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.581

[ Storage condition ]:
Refrigerator (+4°C)

Click to get detail MSDS

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H319-H331-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn,T,Xi:Toxic/Irritant;

[ Risk Phrases ]:
R42

[ Safety Phrases ]:
S36/37/39-S26-S23-S45

[ RIDADR ]:
2206

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2929109000

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2929109000

[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Selective synthesis of a [3]rotaxane consisting of size-complementary components and its stepwise deslippage.

Org. Lett. 14(9) , 2226-9, (2012)

An α-cyclodextrin-based size-complementary [3]rotaxane with an alkylene axle was selectively synthesized in one pot via an end-capping reaction with 2-bromophenyl isocyanate in water. Thermal degradat...

Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development.

Bioorg. Med. Chem. Lett. 16(12) , 3287-91, (2006)

Small molecule antagonists of the vanilloid receptor TRPV1 (also known as VR1) are disclosed. Pyrrolidinyl ureas such as 8 and 15 (SB-705498) emerged as lead compounds following optimisation of the pr...

Discovery of potent and orally bioavailable N,N'-diarylurea antagonists for the CXCR2 chemokine receptor.

Bioorg. Med. Chem. Lett. 14(17) , 4375-8, (2004)

A series of 3-substituted N,N'-diarylureas was prepared and the structure-activity relationship relative to CXCR2 receptor affinity as well as their pharmacokinetic properties were examined. In vitro ...

More Articles