thyronine

Names

[ Name ]:
thyronine

[Synonym ]:
thyronine
(2S)-2-amino-3-[4-(4-hydroxyphenoxy)phenyl]propanoic acid
Tyrosine, O-(4-hydroxyphenyl)-
l-thyronine
Desiodothyroxine
O-(4-Hydroxyphenyl)tyrosine
MFCD00063070
EINECS 216-483-8

Biological Activity

[Description]:

L-Thyronine is a deiodinated thyroxine.

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
477.7±45.0 °C at 760 mmHg

[ Melting Point ]:
259-260℃

[ Molecular Formula ]:
C₁₅H₁₅NO₄

[ Molecular Weight ]:
273.284

[ Flash Point ]:
242.7±28.7 °C

[ Exact Mass ]:
273.100098

[ PSA ]:
92.78000

[ LogP ]:
2.25

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.634

[ Storage condition ]:
-15°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Impact of hydration state and molecular oxygen on the chemical stability of levothyroxine sodium.

Pharm. Dev. Technol. 20(3) , 314-9, (2015)

Levothyroxine sodium is an important medication used primarily for treating patients with hypothyroidism. Levothyroxine sodium tablets have been recalled many times since their 1955 introduction to th...

Immunoexpressions of embryonic and nonembryonic stem cell markers (Nanog, Thy-1, c-kit) and cellular connections (connexin 43 and occludin) on testicular tissue in thyrotoxicosis rat model.

Hum. Exp. Toxicol. 34 , 601-11, (2015)

In this study, possible thyrotoxicosis-related histological changes in testicular tissues of rats with experimentally induced thyrotoxicosis model were evaluated on cellular connections and stem cell ...

A Convenient and Efficient Method to Enrich and Maintain Highly Proliferative Human Fetal Liver Stem Cells.

Rejuvenation Res. 18 , 211-24, (2015)

Pluripotent human hepatic stem cells have broad research and clinical applications, which are, however, restricted by both limited resources and technical difficulties with respect to isolation of ste...