di(N-nitroso)-perhydropyrimidine
Names
[ CAS No. ]:
15973-99-6
[ Name ]:
di(N-nitroso)-perhydropyrimidine
[Synonym ]:
Hexahydro-1,3-dinitrosopyrimidine
1,3-dinitroso-hexahydro-pyrimidine
Pyrimidine,1,3-dinitrosohexahydro
N,N'-Dinitrosohexahydropyrimidine
N,N'-Dinitroso-hexahydro-pyrimidin
1,3-dinitroso-1,3-diazacyclohexane
Dinitroso-hexahydropyrimidin
Chemical & Physical Properties
[ Density]:
1.53g/cm3
[ Boiling Point ]:
406.1ºC at 760 mmHg
[ Molecular Formula ]:
C4H8N4O2
[ Molecular Weight ]:
144.13200
[ Flash Point ]:
199.4ºC
[ Exact Mass ]:
144.06500
[ PSA ]:
65.34000
[ LogP ]:
0.19020
[ Vapour Pressure ]:
1.96E-06mmHg at 25°C
[ Index of Refraction ]:
1.648
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV8925000
- CHEMICAL NAME :
- Pyrimidine, 1,3-dinitrosohexahydro-
- CAS REGISTRY NUMBER :
- 15973-99-6
- BEILSTEIN REFERENCE NO. :
- 0880005
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C4-H8-N4-O2
- MOLECULAR WEIGHT :
- 144.16
- WISWESSER LINE NOTATION :
- T6N CNTJ ANO CNO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - other changes Liver - other changes
- REFERENCE :
- CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 6,57,1979 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13 mg/kg/66W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors
- REFERENCE :
- JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 105,191,1983
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 525 mg/kg/35W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors Liver - tumors
- REFERENCE :
- CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 6,57,1979
Safety Information
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%