3-Fluoro-5-trifluoromethylbenzoic acid

Names

[ Name ]:
3-Fluoro-5-trifluoromethylbenzoic acid

[Synonym ]:
MFCD00061293
α,α,α,5-Tetrafluoro-m-toluic acid
QVR CF EXFFF
3-fluoro-5-trifluoromethylbenzoic acid
3-Fluoro-5-(trifluoromethyl)benzoic acid
Benzoic acid, 3-fluoro-5-(trifluoromethyl)-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
239.6±40.0 °C at 760 mmHg

[ Melting Point ]:
104 °C

[ Molecular Formula ]:
C₈H₄F₄O₂

[ Molecular Weight ]:
208.110

[ Flash Point ]:
98.7±27.3 °C

[ Exact Mass ]:
208.014740

[ PSA ]:
37.30000

[ LogP ]:
3.06

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.459

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2916399090

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Novel small molecule bradykinin B1 receptor antagonists. Part 1: benzamides and semicarbazides.

Bioorg. Med. Chem. Lett. 20(3) , 1225-8, (2010)

The synthesis and SAR of two series of bradykinin B(1) receptor antagonists is described. The benzamide moiety proved to be a suitable replacement for the aryl ester functionality of biaryl based anta...