3-Chloro-1-propanesulfonyl chloride

Names

[ Name ]:
3-Chloro-1-propanesulfonyl chloride

[Synonym ]:
1-Propanesulfonyl chloride, 3-chloro-
EINECS 216-646-3
3-Chloro-1-propanesulfonyl chloride
γ-Chloropropanesulfonyl chloride
MFCD00007463
3-Chloropropane-1-sulfonyl chloride

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
262.1±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃H₆Cl₂O₂S

[ Molecular Weight ]:
177.049

[ Flash Point ]:
92.3±22.6 °C

[ Exact Mass ]:
175.946548

[ PSA ]:
42.52000

[ LogP ]:
1.22

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.477

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TZ6670000

CHEMICAL NAME :: Propanesulfonyl chloride, chloro-

CAS REGISTRY NUMBER :: 1633-82-5

BEILSTEIN REFERENCE NO. :: 1754119

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C3-H6-Cl2-O2-S

MOLECULAR WEIGHT :: 177.05

WISWESSER LINE NOTATION :: WSG3 YG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1160 mg/m3/10M

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report. Volume(issue)/page/year: NDCrc-132,AUG1942

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34;R36/37

[ Safety Phrases ]:
S26-S36/37/39-S45-S24/25

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TZ6670000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Catalytic asymmetric formation of beta-sultams.

Org. Lett. 9 , 2007, (2007)

beta-Sultams, highly strained sulfonyl analogues of beta-lactams, were prepared enantio- and diastereoselectively by tertiary amine catalyzed [2 + 2] cycloaddition reactions. The title compounds are p...

Catalytic enantio- and diastereoselective formation of beta-sultones: ring-strained precursors for enantioenriched beta-hydroxysulfonyl derivatives.

Angew. Chem. Int. Ed. Engl. 46 , 2685, (2007)

Functionalized chiral ionic liquid as recyclable organocatalyst for asymmetric Michael addition to nitrostyrenes. Ni B, et al.

Green Chem. 9(7) , 737-739, (2007)