4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLAN-2-OL

Names

[ Name ]:
4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLAN-2-OL

[Synonym ]:
Pinacol phosphonate
4,4,5,5-TetraMethyl-1,3,2-dioxaphospholane 2-Oxide
hydroxy-2 tetramethyl-4,4,5,5 dioxaphospholanne-1,3,2
hydro-2 oxo-2 tetramethyl-4,4,5,5 dioxaphospholanne-1,3,2
Phosphonic acid pinacol ester
HASPO-1
1,3-dioxa-2-phospha-4,4,5,5-tetramethylcyclopentane
4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-Oxide

Chemical & Physical Properties

[ Boiling Point ]:
179.377ºC at 760 mmHg

[ Melting Point ]:
99-106ºC

[ Molecular Formula ]:
C₆H₁₃O₃P

[ Molecular Weight ]:
164.13900

[ Flash Point ]:
79.028ºC

[ Exact Mass ]:
164.06000

[ PSA ]:
59.00000

[ LogP ]:
1.98010

[ Vapour Pressure ]:
1.278mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H312-H319

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R21

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Air-stable PinP(O)H as preligand for palladium-catalyzed Kumada couplings of unactivated tosylates.

Org. Lett. 8 , 3457, (2006)

[reaction: see text] Air-stable and easily accessible PinP(O)H enables highly efficient palladium-catalyzed Kumada cross-coupling reactions of aryl tosylates. The in situ generated catalyst proved app...