<Suppliers Price>

(2H24)Undecane

Names

[ CAS No. ]:
164858-54-2

[ Name ]:
(2H24)Undecane

[Synonym ]:
(H)Undecane
Undecane-d

Biological Activity

[Description]:

Undecane-d24 is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Choi D, Kang W, Park T. Anti-Allergic and Anti-Inflammatory Effects of Undecane on Mast Cells and Keratinocytes. Molecules. 2020;25(7):1554. Published 2020 Mar 28.  

Chemical & Physical Properties

[ Density]:
0.7±0.1 g/cm3

[ Boiling Point ]:
196.3±3.0 °C at 760 mmHg

[ Molecular Formula ]:
C11D24

[ Molecular Weight ]:
180.456

[ Flash Point ]:
60.0±0.0 °C

[ Exact Mass ]:
180.338440

[ LogP ]:
6.60

[ Vapour Pressure ]:
0.6±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.419

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H304

[ Supplemental HS ]:
Repeated exposure may cause skin dryness or cracking.

[ Precautionary Statements ]:
P301 + P310-P331

[ RIDADR ]:
UN 2330 3 / PGIII

Related Compounds