2-Fluorohexadecanoic acid

Names

[ Name ]:
2-Fluorohexadecanoic acid

[Synonym ]:
2-Fluor-palmitinsaeure
(2RS)-fluorohexadecanoic acid
Hexadecanoic acid,2-fluoro
Hexadecanoic acid, 2-fluoro-
2-Fluorohexadecanoic acid
2-fluoro-hexadecanoic acid

Biological Activity

[Description]:

2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Shabierjiang Jiapaer 1, et al. Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma. Curr Pharm Des. 2020;26(36):4675-4684.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
376.1±12.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₃₁FO₂

[ Molecular Weight ]:
274.414

[ Flash Point ]:
181.3±19.6 °C

[ Exact Mass ]:
274.230804

[ PSA ]:
37.30000

[ LogP ]:
7.03

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.444

Safety Information

[ HS Code ]:
2915900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%