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Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-

Names

[ CAS No. ]:
16620-96-5

[ Name ]:
Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-

[Synonym ]:
2[N]-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
N-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
O-Methylcorypalline
ISOQUINOLINE,1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL
N-Methylheliamine
N-methyl-6,7-dimethoxytetrahydroisoquinoline
6,7-dimethoxy-N-methyl-1,2,3,4-tetrahydroisoquinoline
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinoline

Chemical & Physical Properties

[ Density]:
1.061g/cm3

[ Boiling Point ]:
300.1ºC at 760mmHg

[ Molecular Formula ]:
C12H17NO2

[ Molecular Weight ]:
207.26900

[ Flash Point ]:
108.7ºC

[ Exact Mass ]:
207.12600

[ PSA ]:
21.70000

[ LogP ]:
1.62960

[ Vapour Pressure ]:
0.00115mmHg at 25°C

[ Index of Refraction ]:
1.527

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX5018510
CHEMICAL NAME :
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-
CAS REGISTRY NUMBER :
16620-96-5
BEILSTEIN REFERENCE NO. :
0011592
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H17-N-O2
MOLECULAR WEIGHT :
207.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - central sympatholytic
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,244,1948

Synthetic Route

Precursor & DownStream


Related Compounds