DiSBAC10

Names

[ Name ]:
DiSBAC10

[Synonym ]:
disbac10
4,6(1H,5H)-Pyrimidinedione, 5,5'-[(1E)-1-propen-1-yl-3-ylidene]bis[1,3-didecyldihydro-2-thioxo-
5,5'-[(1E)-1-Propen-1-yl-3-ylidene]bis(1,3-didecyl-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione)

Biological Activity

[Description]:

DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
844.6±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅₁H₈₈N₄O₄S₂

[ Molecular Weight ]:
885.40

[ Flash Point ]:
464.6±37.1 °C

[ Exact Mass ]:
884.624695

[ PSA ]:
145.42000

[ LogP ]:
16.84

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.551