4-Maleimidobenzoic acid

Names

[ Name ]:
4-Maleimidobenzoic acid

[Synonym ]:
4-(N-Maleimido)benzoic acid
MFCD00458571
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-benzoic acid
Benzoic acid, 4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
EINECS 241-117-9
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
4-Maleimidobenzoic acid

Biological Activity

[Description]:

4-Maleimidobenzoic acid is a protein crosslinker. 4-Maleimidobenzoic acid can be used to synthesis maleimidobenzoyl spacers[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Lau A, et, al. Conjugation of doxorubicin to monoclonal anti-carcinoembryonic antigen antibody via novel thiol-directed cross-linking reagents. Bioorg Med Chem. 1995 Oct;3(10):1299-304.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
447.1±28.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₇NO₄

[ Molecular Weight ]:
217.178

[ Flash Point ]:
224.2±24.0 °C

[ Exact Mass ]:
217.037506

[ PSA ]:
74.68000

[ LogP ]:
0.77

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.669

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36

[ Safety Phrases ]:
26

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%