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E4CPG

Names

[ CAS No. ]:
170846-89-6

[ Name ]:
E4CPG

[Synonym ]:
Benzeneacetic acid, α-amino-4-carboxy-α-ethyl-
4-(1-Amino-1-carboxypropyl)benzoic acid

Biological Activity

[Description]:

E4CPG is a novel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG .

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Sekiyama N et al. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptorsubtypes. Br J Pharmacol, 1996 Apr, 117(7):1493-503.

[2]. Bedingfield JS et al. Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). Br J Pharmacol. 1995 Dec;116(8):3323-9.


[Related Small Molecules]

mavoglurant | L-Glutamine | CTEP (RO4956371) | LY 354740 | L-(+)Sodium glutamate | ADX-88178 | MPEP (Hydrochloride) | FITM | (S)-MCPG | Basimglurant | LY341495 | Dipraglurant | JNJ-40411813 | LY404039 | JNJ 16259685

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
431.3±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H13NO4

[ Molecular Weight ]:
223.225

[ Flash Point ]:
214.7±27.3 °C

[ Exact Mass ]:
223.084457

[ LogP ]:
1.50

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.594

[ Storage condition ]:
2-8℃