L-Sepiapterin
Names
[ CAS No. ]:
17094-01-8
[ Name ]:
L-Sepiapterin
[Synonym ]:
2-amino-6-(2-hydroxy-propionyl)-7,8-dihydro-3H-pteridin-4-one
MFCD00210214
1-(2-amino-7,8-dihydro-4-hydroxy-6-pteridinyl)-2-hydroxy-1-Propanone
4(3H)-Pteridinone, 2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-
2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-4(1H)-Pteridinone
2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-4(1H)Pteridinone
(S)-2-amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-Pteridinone
Sepiapterine
L-Sepiapterin
Sepiapterin,S-()-2-Amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-pteridinone,L-Sepiapterin
2-Amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-4(1H)-pteridinone
Sepiapterin
2-Amino-6-L-lactoyl-7,8-dihydro-3H-pteridin-4-on
2-amino-6-(2-hydroxypropanoyl)-7,8-dihydro-1H-pty oeridin-4-one
2-AMINO-7,8-DIHYDRO-6-(2S-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE
2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-1H-pteridin-4-one
2-Amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydropteridin-4(3H)-one
S-(−)-2-Amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-pteridinone
S(-)-2-AMINO-7,8-DIHYDRO-6-(2-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE
2-amino-6-L-lactoyl-7,8-dihydro-3H-pteridin-4-one
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
[In Vitro]
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
1.9±0.1 g/cm3
[ Boiling Point ]:
448.1ºC at 760 mmHg
[ Melting Point ]:
> 275 °C (lit.)
[ Molecular Formula ]:
C9H11N5O3
[ Molecular Weight ]:
237.215
[ Flash Point ]:
224.8ºC
[ Exact Mass ]:
237.086182
[ PSA ]:
133.46000
[ LogP ]:
-3.93
[ Vapour Pressure ]:
6.54E-10mmHg at 25°C
[ Index of Refraction ]:
1.822
[ Storage condition ]:
20°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
24/25
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2933990090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Mol. Endocrinol. 29 , 1123-33, (2015)
We have recently shown that angiotensin II-mediated uncoupling of endothelial nitric oxide synthase (eNOS) contributes to endothelial dysfunction in streptozotocin-induced type 1 diabetes mellitus. Ho...
Sulfa drugs inhibit sepiapterin reduction and chemical redox cycling by sepiapterin reductase.J. Pharmacol. Exp. Ther. 352(3) , 529-40, (2015)
Sepiapterin reductase (SPR) catalyzes the reduction of sepiapterin to dihydrobiopterin (BH2), the precursor for tetrahydrobiopterin (BH4), a cofactor critical for nitric oxide biosynthesis and alkylgl...
Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation.Sci. Signal. 8 , ra81, (2015)
Endothelial nitric oxide synthase (eNOS) catalyzes the conversion of l-arginine and molecular oxygen into l-citrulline and nitric oxide (NO), a gaseous second messenger that influences cardiovascular ...