2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol,3,4,4a,5,16a,17,18,19-octahydro-9,21,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-(9CI)
Names
[ CAS No. ]:
17132-74-0
[ Name ]:
2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol,3,4,4a,5,16a,17,18,19-octahydro-9,21,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-(9CI)
[Synonym ]:
Homothalicrine
N-methyl-daphnandrine
homaromoline
Thalrugosamine
homothalictrine
6,6',12'-trimethoxy-2,2'-dimethyl-oxyacanthan-7-ol
(+)-homoaromoline
Oxyacanthan-7-ol,6,6',12'-trimethoxy-2,2'-dimethyl
Chemical & Physical Properties
[ Density]:
1.204g/cm3
[ Boiling Point ]:
709.7ºC at 760mmHg
[ Molecular Formula ]:
C37H40N2O6
[ Molecular Weight ]:
608.72300
[ Flash Point ]:
383ºC
[ Exact Mass ]:
608.28900
[ PSA ]:
72.86000
[ LogP ]:
6.73520
[ Vapour Pressure ]:
8.25E-21mmHg at 25°C
[ Index of Refraction ]:
1.601
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MS9272000
- CHEMICAL NAME :
- Homoaromoline
- CAS REGISTRY NUMBER :
- 17132-74-0
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C37-H40-N2-O6
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 24500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 15,513,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6370 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 15,513,1980