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1,2-Propanediol,3-(1-methylethoxy)-

Names

[ CAS No. ]:
17226-43-6

[ Name ]:
1,2-Propanediol,3-(1-methylethoxy)-

[Synonym ]:
3-Isopropoxy-propan-1,2-diol
3-Isopropoxy-1,2-propanediol
2,3-dihydroxypropyl 2-propyl ether
3-Isopropoxypropane-1,2-diol
O1-Isopropyl-glycerin

Chemical & Physical Properties

[ Density]:
1.034g/cm3

[ Boiling Point ]:
235.8ºC at 760mmHg

[ Molecular Formula ]:
C6H14O3

[ Molecular Weight ]:
134.17400

[ Flash Point ]:
96.4ºC

[ Exact Mass ]:
134.09400

[ PSA ]:
49.69000

[ Vapour Pressure ]:
0.00444mmHg at 25°C

[ Index of Refraction ]:
1.445

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TY7900000
CHEMICAL NAME :
1,2-Propanediol, 3-isopropoxy-
CAS REGISTRY NUMBER :
17226-43-6
BEILSTEIN REFERENCE NO. :
1736326
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H14-O3
MOLECULAR WEIGHT :
134.20
WISWESSER LINE NOTATION :
Q1YQ1OY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 2,574,1950
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 2,574,1950 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8200 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 8,477,1949
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
201 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 2,574,1950
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974

Safety Information

[ HS Code ]:
2909499000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%


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