(1,4-dioxidoquinoxaline-2,3-diyl)dimethanol
Names
[ CAS No. ]:
17311-31-8
[ Name ]:
(1,4-dioxidoquinoxaline-2,3-diyl)dimethanol
[Synonym ]:
Quinoxalinium, 1,4-dihydro-4-hydroxy-2,3-bis(hydroxymethyl)-1-oxo-, inner salt
2,3-Quinoxalinedimethanol 1,4-dioxide
2,3-dihydroxymethylquinoxaline 1,4-di-N-oxide
2,3-Bis(hydroxymethyl)-1-oxoquinoxalin-1-ium-4(1H)-olate
DIOXIDINE
Dioxidin
(1,4-dioxidoquinoxaline-2,3-diyl)dimethanol
Dioxydine
1,4-Di-N-oxide of dihydroxymethylquinoxaline
Chemical & Physical Properties
[ Density]:
1.5
[ Melting Point ]:
171-172ºC
[ Molecular Formula ]:
C10H10N2O4
[ Molecular Weight ]:
222.197
[ Exact Mass ]:
222.064056
[ PSA ]:
91.38000
[ LogP ]:
0.68140
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VD1900000
- CHEMICAL NAME :
- 2,3-Quinoxalinedimethanol, 1,4-dioxide
- CAS REGISTRY NUMBER :
- 17311-31-8
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 24
- MOLECULAR FORMULA :
- C10-H10-N2-O4
- MOLECULAR WEIGHT :
- 222.22
- WISWESSER LINE NOTATION :
- T66 BN ENJ BO C1Q D1Q EO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Dominant lethal test
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Dominant lethal test
- TYPE OF TEST :
- Dominant lethal test
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 270 mg/kg
- REFERENCE :
- SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 14,640,1978
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%