2-Propenal, 3- (4-nitrophenyl)-

Names

[ Name ]:
2-Propenal, 3- (4-nitrophenyl)-

[Synonym ]:
MFCD00007379
2-Propenal, 3- (4-nitrophenyl)-
3-(4-Nitrophenyl)-2-propenal
(2E)-3-(4-Nitrophenyl)acrylaldehyde
2-Propenal, 3-(4-nitrophenyl)-, (2E)-
(2E)-3-(4-Nitrophenyl)-2-propenal
4-NITROCINNAMALDEHYDE
trans-4-Nitrocinnamaldehyde
EINECS 217-076-8

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
311.6±17.0 °C at 760 mmHg

[ Melting Point ]:
140-143 °C(lit.)

[ Molecular Formula ]:
C₉H₇NO₃

[ Molecular Weight ]:
177.157

[ Flash Point ]:
151.6±13.7 °C

[ Exact Mass ]:
177.042587

[ PSA ]:
62.89000

[ LogP ]:
1.90

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.618

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD6650000

CHEMICAL NAME :: Cinnamaldehyde, p-nitro-

CAS REGISTRY NUMBER :: 1734-79-8

BEILSTEIN REFERENCE NO. :: 1565424

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H7-N-O3

MOLECULAR WEIGHT :: 177.17

WISWESSER LINE NOTATION :: WNR D1U1VH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,145,1954

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
GD6650000

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

Reactivity at the substrate activation site of yeast pyruvate decarboxylase: inhibition by distortion of domain interactions.

Biochemistry 37(5) , 1245-55, (1998)

The residue C221 on pyruvate decarboxylase (EC. 4.1.1.1) from Saccharomyces cerevisiae has been shown to be the site where the substrate activation cascade is triggered [Baburina et al. (1994) Biochem...

Genotoxicity of p-nitrocinnamaldehyde and related alpha, beta-unsaturated carbonyl compounds in two bacterial assays.

Mutagenesis 6(4) , 261-9, (1991)

Seventeen cinnamaldehydes, cinnamic acids, 2-furylacroleins and related compounds were tested in the Salmonella preincubation reversion assay and in the SOS chromotest. Of eight compounds containing n...